Rhodes KE, Gekas C, Wang Y, Lux CT, Francis CS, Chan DN, Conway S, Orkin SH, Yoder MC, Mikkola HK. The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation. Cell Stem Cell 2008 2:252

Magnusson M and Mikkola HK. Hematopoietic Stem Cells in Transit - Where’s the Niche? Cell Stem Cell 2008, 2:302

Schenke-Layland K, Rhodes K, Angelis E, Butylkova Y, Heydarkhan-Hagvall S, Gekas C, Zhang R, Goldhaber J, Mikkola HK, Plath K and MacLellan WR. Reprogrammed fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells 2008 in press

Laiho E, Ignatius J, Mikkola H, Yee VC, Teller DC, Niemi K-M, Saarialho-Kere U, Kere J and Palotie A. Transglutaminase 1 mutations in autosomal recessive congenital icthyosis: private and recurrent mutations in an isolated population. Am J Hum Genet 1997, 61:529

Mikkola H, Muszbek L, Hämäläinen E, Haramura G, Jalanko A and Palotie A. Molecular mechanisms of mutations in FXIII deficiency: in vitro expression in COS-cells demonstrates intracellular degradation of the mutant proteins. Thromb Haemost 1997, 78:1068

Mikkola H, Muszbek L, Laiho E, Syrjälä M, Hämäläinen E, Haramura G, Salmi T, Peltonen L and Palotie A. Molecular mechanism of a mild phenotype in coagulation factor FXIII deficiency: a splicing mutation permitting partial correct splicing of FXIII A-subunit mRNA. Blood 1997, 88:1279

Muszbek L, Adany R and Mikkola H. Novel aspects of blood coagulation factor XIII. Critical reviews in clinical laboratory sciences 1996, 33:357.

Mikkola H and Palotie A. Gene defects in factor XIII deficiency. Seminars in Thrombosis and Haemostasis 1996;22:393-8.

Mikkola H, Yee VC, Syrjälä M, Seitz R, Egbring R, Petrini P, Ljung R, Ingerslev J, Teller DC, Peltonen L and Palotie A. Four novel mutations in coagulation factor XIII deficiency: Consequences to expression and structure of the A-subunit. Blood 1996, 87:141

Mikkola H, Syrjälä M, Rasi V, Vahtera E, Peltonen L and Palotie A. Deficiency in the A-subunit of coagulation factor XIII: Two novel point mutations demonstrate different effects on transcript levels. Blood 1994, 84:517

Wartiovaara U, Perola M, Mikkola H, Tötterman K-J, Salonen V, Tikkanen M, Grant P, Vartiainen E, Karhunen P, Peltonen L and Palotie A. Association of FXIII Val34Leu with decreased risk of myocardial infarction in Finnish males. Atherosclerosis 1999, 104:295

Heliö T, Wartiovaara U, Halme L, Turunen U-M,  Mikkola H, Palotie A, Färkkilä M and Kontula K. Arg506->Gln factor V mutation and Val34->Leu factor XIII polymorphism in inflammatory bowel disease. Scand J Gastroent 1999, 2:170

Wartiovaara U, Mikkola H, Szoke G, Haramura G, Karpati L, Balogh I, Lassila R, Muszbek L and Palotie A. Effect of Val34Leu polymorphism on the activation of the coagulation factor XIII-A. Thromb Haemost 2000, 84:595

Kohler H, Stickland M, Ossei-Gerning N, Carter A, Mikkola H and Grant P. Association of a common polymorphism in the factor XIII gene with myocardial infarction. Thromb Haemost 1998, 79:8

Wartiovaara U, Salven P, Mikkola H, Lassila R, Joukov V, Ristimäki A, Orpana A, Heikinheimo M, Joensuu H, Alitalo K and Palotie A. Peripheral platelets express VEGF and VEGF-C which are released during platelet activation. Thromb Haemost 1998, 80:171

Hamaguchi I, Panagopoulos I, Andersson E, Woods N-B, Fahlman C, Mikkola H, Carlsson L, Zufferey R, Trono D and Karlsson S. Lentiviral gene expression during ES cell derived hematopoietic development in vitro. J Virol 2000, 74:10778

Woods NB, Fahlman C, Mikkola H, Hamaguchi I, Olsson K, Zufferey R, Jacobsen SE, Trono D and Karlsson S. Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells. Blood 2000, 96:3725

Mikkola H, Woods NB, Sjogren M, Helgadottir H, Hamaguchi I, Jacobsen SE, Trono D and Karlsson S. Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells.  J Virol 2000, 74:11911

Balogh I, Szoke G, Karpati L, Wartiovaara U, Katona E, Komaromi I, Haramura G, Pfliegler G, Mikkola H and Muszbek L Val34Leu polymorphism of plasma factor XIII: biochemistry and epidemiology in familial thrombophilia. Blood 2000;96:2479

Loewy A, McDonagh J, Mikkola H, Teller D and Yee V. Structure and Function of Factor XIII in Colman, Hirsh, Marder, Clowes, George, editors, Hemostasis and Thrombosis: Basic principles and Clinical Practise 2000, p233

Mikkola HKA and Orkin SH. Gene targeting and transgenic strategies for analysis of hematopoietic development in the mouse. In Baron M, editor, Methods on Molecular Medicine 2004, 826:3

Schlaeger TM, Schuh A, Flitter S, Fisher A, Mikkola H, Orkin SH, Vyas P and Porcher C. Decoding Hematopoietic Specificity in the Helix-Loop-Helix Domain of the Transcription Factor SCL/Tal-1 Mol Cell Biol 2004, 24:7491

Mikkola HKA, Klintman J, Yang H, Hock H, Schlaeger TM, Fujiwara, Y and Orkin SH. Hematopoietic stem cells retain long term reconstitution activity and multipotency in the absence of the stem cell leukemia (SCL/tal1) gene. Nature 2003, 421:547

Mikkola HKA, Fujiwara Y, Traver D, Schlaeger TM and Orkin SH. CD41 expression marks the initiation of definitive hematopoiesis in the mouse embryo. Blood 2003, 101:508

Mikkola HKA and Orkin SH. The search for the hemangioblast. J Hematother Stem Cell Res 2002, 11:9

Woods N-B, Mikkola H, Nilsson E, Olsson K, Trono D and Karlsson S. Lentiviral-Mediated Gene Transfer into Hematopoietic Stem Cells. J Intern Med 2001, 249:339

Martinez-Agosto JA, Mikkola HK, Hartenstein V, Banerjee U. The hematopoietic stem cell and its niche: a comparative view. Genes Dev 2007 21:3044

Schenke-Layland K, Angelis E, Rhodes K, Hagvall SH, Mikkola HKA and MacLellan WR. Collagen IV induces trophoectoderm differentiation of mouse embryonic stem cells. Stem Cells, 2007 (E-publication March 15)

Mikkola HKA and Orkin SH. The journey of developing hematopoietic stem cells. Development 2006, 133: 3733

Teitell MA and Mikkola HKA. Transcriptional activators, repressor and epigenetic modifiers controlling hematopoietic stem cell development. Pediatric Res 2006;59:33

Mikkola HKA, Gekas C, Orkin SH and Dieterlen-Lievre F. Placenta as a site for hematopoietic stem cell development. Exp Hematol 2005, 33:1048

Gekas C, Dieterlen-Lievre F, Orkin SH and Mikkola HKA. Placenta is a niche for hematopoietic stem cells. Devl Cell 2005, 8:365

Schlaeger TM, Mikkola HKA, Gekas C, Helgadottir HB and Orkin SH. Tie2Cre-mediated gene ablation defines the Stem Cell Leukemia gene (SCL/tal1)-dependent window during hematopoietic stem cell development. Blood 2005, 5:3871